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Chemical, Target, and Bioactive Properties of Allosteric Modulation
Allosteric modulators are ligands for proteins that exert their effects via a different binding site than the natural (orthosteric) ligand site and hence form a conceptually distinct class of ligands for a target of interest. Here, the physicochemical and structural features of a large set of allost...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3974644/ https://ncbi.nlm.nih.gov/pubmed/24699297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003559 |
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