Liver fat accumulation is associated with reduced hepatic insulin extraction and beta cell dysfunction in healthy older individuals

BACKGROUND: There is a well-established association between type 2 diabetes and non-alcoholic fatty liver disease (NAFLD) secondary to excess accumulation of intrahepatic lipid (IHL), but the mechanistic basis for this association is unclear. Emerging evidence suggests that in addition to being asso...

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Autores principales: Finucane, Francis M, Sharp, Stephen J, Hatunic, Mensud, Sleigh, Alison, De Lucia Rolfe, Ema, Aihie Sayer, Avan, Cooper, Cyrus, Griffin, Simon J, Wareham, Nicholas J
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974597/
https://ncbi.nlm.nih.gov/pubmed/24669786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-5996-6-43
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