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Hydrogen Peroxide Activation of ERK5 Confers Resistance to Jurkat Cells Against Apoptosis Induced by the Extrinsic Pathway
Reactive oxygen species (ROS) including hydrogen peroxide (H(2)O(2)) exhibit both pro-survival and pro-death signaling in leukemic cells. We examined the effect of exogenous H(2)O(2) on Fas ligand (FasL) -induced apoptosis in Jurkat cells. H(2)O(2) applied prior to (pre-conditioning) and during (pos...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3974591/ https://ncbi.nlm.nih.gov/pubmed/24462874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2014.01.058 |
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