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Variability and resistance mutations in the hepatitis C virus NS3 protease in patients not treated with protease inhibitors

The goal of treatment of chronic hepatitis C is to achieve a sustained virological response, which is defined as exhibiting undetectable hepatitis C virus (HCV) RNA levels in serum following therapy for at least six months. However, the current treatment is only effective in 50% of patients infected...

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Hlavní autoři: Zeminian, Luciana Bonome, Padovani, Juliana Lara, Corvino, Sílvia Maria, Silva, Giovanni Faria, Pardini, Maria Inês de Moura Campos, Grotto, Rejane Maria Tommasini
Médium: Artigo
Jazyk:Inglês
Vydáno: Instituto Oswaldo Cruz, Ministério da Saúde 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974320/
https://ncbi.nlm.nih.gov/pubmed/23440108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S0074-02762013000100002
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