Differences in structural elements of Bcr-Abl oncoprotein isoforms in Chronic Myelogenous Leukemia

in silico modeling, using Psipred and ExPASy servers was employed to determine the structural elements of Bcr-Abl oncoprotein (p210(BCR-ABL)) isoforms, b2a2 and b3a2, expressed in Chronic Myelogenous Leukemia (CML). Both these proteins are tyrosine kinases having masses of 210-kDa and differing only...

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Autori principali: Hai, Abdul, Kizilbash, Nadeem A, Zaidi, Syeda Huma H, Alruwaili, Jamal, Shahzad, Khuram
Natura: Artigo
Lingua:Inglês
Pubblicazione: Biomedical Informatics 2014
Soggetti:
Hypothesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974235/
https://ncbi.nlm.nih.gov/pubmed/24748748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630010108
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