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Temporal linkage between the phenotypic and genomic responses to caloric restriction

Caloric restriction (CR), the consumption of fewer calories while avoiding malnutrition, decelerates the rate of aging and the development of age-related diseases. CR has been viewed as less effective in older animals and as acting incrementally to slow or prevent age-related changes in gene express...

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Main Authors: Dhahbi, Joseph M., Kim, Hyon-Jeen, Mote, Patricia L., Beaver, Robert J., Spindler, Stephen R.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC397416/
https://ncbi.nlm.nih.gov/pubmed/15044709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0305300101
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