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The Vibrio cholerae diguanylate cyclase VCA0965 has an AGDEF active site and synthesizes cyclic di-GMP

BACKGROUND: Diguanylate cyclases (DGCs) regulate biofilm formation and motility in bacteria by synthesizing the second messenger cyclic di-GMP (c-di-GMP) in response to environmental stimuli. DGC enzymatic activity is believed to be dependent on the presence of a GG(D/E)EF active site motif, however...

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Bibliografiske detaljer
Main Authors: Hunter, Jessica L, Severin, Geoffrey B, Koestler, Benjamin J, Waters, Christopher M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974145/
https://ncbi.nlm.nih.gov/pubmed/24490592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-14-22
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