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Deletion of p47(phox) Attenuates Angiotensin II–Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E–Deficient Mice

BACKGROUND: Angiotensin II (Ang II) contributes to vascular pathology in part by stimulating NADPH oxidase activity, leading to increased formation of superoxide (O(2)(–)). We reported that O(2)(–) levels, NADPH oxidase activity, and expression of the p47(phox) subunit of NADPH oxidase are increased...

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Detalhes bibliográficos
Main Authors: Thomas, Manesh, Gavrila, Dan, McCormick, Michael L., Miller, Francis J., Daugherty, Alan, Cassis, Lisa A., Dellsperger, Kevin C., Weintraub, Neal L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974117/
https://ncbi.nlm.nih.gov/pubmed/16864727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.105.607168
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