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Effect of sulfide structure on enantioselectivity in catalytic asymmetric epoxidation of aldehydes: Mechanistic insights and implications

Bridged bicyclic sulfide 1 was originally found to provide high levels of asymmetric induction in sulfur ylide-mediated epoxidations. This sulfide possesses chirality in the [2.2.1] thioether moiety and the [2.2.1] camphor-derived carbocyclic moiety. To determine whether the optimal sulfide had been...

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Autors principals: Aggarwal, Varinder K., Charmant, Jonathan, Dudin, Leo, Porcelloni, Marina, Richardson, Jeffery
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC397406/
https://ncbi.nlm.nih.gov/pubmed/15034181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307559101
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