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Exploiting SNP Correlations within Random Forest for Genome-Wide Association Studies

The primary goal of genome-wide association studies (GWAS) is to discover variants that could lead, in isolation or in combination, to a particular trait or disease. Standard approaches to GWAS, however, are usually based on univariate hypothesis tests and therefore can account neither for correlati...

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Detalhes bibliográficos
Main Authors: Botta, Vincent, Louppe, Gilles, Geurts, Pierre, Wehenkel, Louis
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973686/
https://ncbi.nlm.nih.gov/pubmed/24695491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093379
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