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Direct, Acute Effects of Klotho and FGF23 on Vascular Smooth Muscle and Endothelium
Chronic kidney disease (CKD) is regarded as a state of Klotho deficiency and FGF23 excess. In patients with CKD a strong association has been found between increased serum FGF23 and mortality risk, possibly via enhanced atherosclerosis, vascular stiffness, and vascular calcification. The aim of this...
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Autores principales: | , , , , , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3973676/ https://ncbi.nlm.nih.gov/pubmed/24695641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093423 |
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