Immunohistochemical detection of cytoplasmic LC3 puncta in human cancer specimens

Autophagy is an evolutionarily conserved catabolic process that involves the entrapment of cytoplasmic components within characteristic vesicles for their delivery to and degradation within lysosomes. Alterations in autophagic signaling are found in several human diseases including cancer. Here, we...

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Main Authors: Ladoire, Sylvain, Chaba, Kariman, Martins, Isabelle, Sukkurwala, Abdul Qader, Adjemian, Sandy, Michaud, Mickaël, Poirier-Colame, Vichnou, Andreiuolo, Felipe, Galluzzi, Lorenzo, White, Eileen, Rosenfeldt, Mathias, Ryan, Kevin M., Zitvogel, Laurence, Kroemer, Guido
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2012
Fag:
Basic Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973657/
https://ncbi.nlm.nih.gov/pubmed/22647537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.20353
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