TRAIL-R1 Is a Negative Regulator of Pro-Inflammatory Responses and Modulates Long-Term Sequelae Resulting from Chlamydia trachomatis Infections in Humans

The immune system eliminates Chlamydia trachomatis infection through inflammation. However, uncontrolled inflammation can enhance pathology. In mice, TNF-related apoptosis-inducing ligand receptor (TRAIL-R), known for its effects on apoptosis, also regulates inflammation. In humans, the four homolog...

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Detalhes bibliográficos
Main Authors: Al-Kuhlani, Mufadhal, Rothchild, James, Pal, Sukumar, de la Maza, Luis M., Ouburg, Sander, Morré, Servaas A., Dean, Deborah, Ojcius, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973638/
https://ncbi.nlm.nih.gov/pubmed/24695582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093939
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