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Lesions of the Lateral Habenula Increase Voluntary Ethanol Consumption and Operant Self-Administration, Block Yohimbine-Induced Reinstatement of Ethanol Seeking, and Attenuate Ethanol-Induced Conditioned Taste Aversion

The lateral habenula (LHb) plays an important role in learning driven by negative outcomes. Many drugs of abuse, including ethanol, have dose-dependent aversive effects that act to limit intake of the drug. However, the role of the LHb in regulating ethanol intake is unknown. In the present study, w...

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Detalhes bibliográficos
Main Authors: Haack, Andrew K., Sheth, Chandni, Schwager, Andrea L., Sinclair, Michael S., Tandon, Shashank, Taha, Sharif A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973636/
https://ncbi.nlm.nih.gov/pubmed/24695107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092701
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