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Protection against gram-negative bacteremia and endotoxemia with human monoclonal IgM antibodies.

Hybridomas producing human monoclonal IgM antibodies (mAbs) against bacterial lipopolysaccharide (LPS) were generated by fusion of B lymphocytes from sensitized human spleen with heteromyeloma cells. The splenocytes were from patients undergoing splenectomy during staging for Hodgkin disease after v...

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Main Authors: Teng, N N, Kaplan, H S, Hebert, J M, Moore, C, Douglas, H, Wunderlich, A, Braude, A I
Formato: Artigo
Idioma:Inglês
Publicado: 1985
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC397358/
https://ncbi.nlm.nih.gov/pubmed/3856860
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