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Host-Directed Therapeutics for Tuberculosis: Can We Harness the Host?

SUMMARY: Treatment of tuberculosis (TB) remains challenging, with lengthy treatment durations and complex drug regimens that are toxic and difficult to administer. Similar to the vast majority of antibiotics, drugs for Mycobacterium tuberculosis are directed against microbial targets. Although more...

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Detalhes bibliográficos
Main Authors: Hawn, Thomas R., Matheson, Alastair I., Maley, Stephen N., Vandal, Omar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973381/
https://ncbi.nlm.nih.gov/pubmed/24296574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.00032-13
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