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RNase L restricts the mobility of engineered retrotransposons in cultured human cells
Retrotransposons are mobile genetic elements, and their mobility can lead to genomic instability. Retrotransposon insertions are associated with a diverse range of sporadic diseases, including cancer. Thus, it is not a surprise that multiple host defense mechanisms suppress retrotransposition. The 2...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3973342/ https://ncbi.nlm.nih.gov/pubmed/24371271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1308 |
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