AUF1 contributes to Cryptochrome1 mRNA degradation and rhythmic translation

In the present study, we investigated the 3′ untranslated region (UTR) of the mouse core clock gene cryptochrome 1 (Cry1) at the post-transcriptional level, particularly its translational regulation. Interestingly, the 3′UTR of Cry1 mRNA decreased its mRNA levels but increased protein amounts. The 3...

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Hlavní autoři: Lee, Kyung-Ha, Kim, Sung-Hoon, Kim, Hyo-Jin, Kim, Wanil, Lee, Hwa-Rim, Jung, Youngseob, Choi, Jung-Hyun, Hong, Ka Young, Jang, Sung Key, Kim, Kyong-Tai
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Gene Regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973335/
https://ncbi.nlm.nih.gov/pubmed/24423872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1379
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