Eradication of established intracranial rat gliomas by transforming growth factor beta antisense gene therapy.

Like human gliomas, the rat 9L gliosarcoma secretes the immunosuppressive transforming growth factor beta (TGF-beta). Using the 9L model, we tested our hypothesis that genetic modification of glioma cells to block TGF-beta expression may enhance their immunogenicity and make them more suitable for a...

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Detalhes bibliográficos
Main Authors: Fakhrai, H, Dorigo, O, Shawler, D L, Lin, H, Mercola, D, Black, K L, Royston, I, Sobol, R E
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC39733/
https://ncbi.nlm.nih.gov/pubmed/8610141
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