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Light Damage in Abca4 and Rpe65(rd12) Mice

PURPOSE. Bisretinoids form in photoreceptor cells and accumulate in retinal pigment epithelium (RPE) as lipofuscin. To examine the role of these fluorophores as mediators of retinal light damage, we studied the propensity for light damage in mutant mice having elevated lipofuscin due to deficiency i...

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Autori principali: Wu, Li, Ueda, Keiko, Nagasaki, Taka, Sparrow, Janet R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Association for Research in Vision and Ophthalmology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973190/
https://ncbi.nlm.nih.gov/pubmed/24576873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-13867
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