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Na(v)-igating through a complex landscape: SCN10A and cardiac conduction

Genome-wide association studies (GWAS) have implicated SCN10A, which encodes a nociceptor-associated voltage-gated sodium channel subunit, as a modulator of cardiac conduction; however, this role has traditionally been ascribed to SCN5A, which is highly expressed in cardiac muscle. SCN10A is believe...

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Detalhes bibliográficos
Main Authors: Park, David S., Fishman, Glenn I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973102/
https://ncbi.nlm.nih.gov/pubmed/24642462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75240
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