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Na(v)-igating through a complex landscape: SCN10A and cardiac conduction
Genome-wide association studies (GWAS) have implicated SCN10A, which encodes a nociceptor-associated voltage-gated sodium channel subunit, as a modulator of cardiac conduction; however, this role has traditionally been ascribed to SCN5A, which is highly expressed in cardiac muscle. SCN10A is believe...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3973102/ https://ncbi.nlm.nih.gov/pubmed/24642462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75240 |
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