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Correction of hyperglycemia with phloridzin restores the glucagon response to glucose in insulin-deficient dogs: implications for human diabetes.

In insulin-deprived alloxan-induced diabetic dogs with severe hyperglycemia and marked hyperglucagonemia, glucagon was not suppressed by intravenous infusion of glucose at a progressively increasing rate up to 24 mg/kg of body weight per min. However, when the hyperglycemia was corrected by phloridz...

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Main Authors: Starke, A, Grundy, S, McGarry, J D, Unger, R H
Format: Artigo
Jezik:Inglês
Izdano: 1985
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC397300/
https://ncbi.nlm.nih.gov/pubmed/3883362
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