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Loss of polymorphic restriction fragments in malignant melanoma: implications for tumor heterogeneity.

Loss of genetic material at certain chromosomal sites is implicated in the etiology of retinoblastoma and Wilms tumor. Whether specific chromosomal deletions are associated with other types of human cancer needs to be explored. We have examined 24 melanoma cell lines, derived from 21 patients with n...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Dracopoli, N C, Houghton, A N, Old, L J
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1985
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397284/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2983346/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.5.1470
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