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β-Globin Matrix Attachment Region Improves Stable Genomic Expression of the Sleeping Beauty Transposon

The liver is an attractive target for gene therapy due to its extensive capability for protein production and the numerous diseases resulting from a loss of gene function it normally provides. The Sleeping Beauty Transposon (SB-Tn)(1) system is a non-viral vector capable of delivering and mediating...

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Bibliografiska uppgifter
Huvudupphovsmän: Sjeklocha, Lucas, Chen, Yixin, Daly, Meghan C., Steer, Clifford J., Kren, Betsy T.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972825/
https://ncbi.nlm.nih.gov/pubmed/21520245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23159
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