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β-Globin Matrix Attachment Region Improves Stable Genomic Expression of the Sleeping Beauty Transposon

The liver is an attractive target for gene therapy due to its extensive capability for protein production and the numerous diseases resulting from a loss of gene function it normally provides. The Sleeping Beauty Transposon (SB-Tn)(1) system is a non-viral vector capable of delivering and mediating...

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Detalhes bibliográficos
Main Authors: Sjeklocha, Lucas, Chen, Yixin, Daly, Meghan C., Steer, Clifford J., Kren, Betsy T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972825/
https://ncbi.nlm.nih.gov/pubmed/21520245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23159
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