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Calcium channel antagonists inhibit the acrosome reaction and bind to plasma membranes of sea urchin sperm.

As a prerequisite to fertilization, sea urchin sperm undergo an acrosome reaction that is mediated in part by increased permeability to Ca2+, with an attendant rapid, massive intracellular Ca2+ accumulation. The acrosome reaction is inhibited by Ca2+ channel antagonists, including verapamil, D600, a...

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Bibliografiska uppgifter
Huvudupphovsmän: Kazazoglou, T, Schackmann, R W, Fosset, M, Shapiro, B M
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1985
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC397282/
https://ncbi.nlm.nih.gov/pubmed/3856274
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