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Syntenin increases the invasiveness of small cell lung cancer cells by activating p38, AKT, focal adhesion kinase and SP1

Syntenin is a PDZ domain-containing adaptor protein that has been recently shown to regulate migration and invasion in several tumors. Small cell lung cancer (SCLC) is notorious for its invasiveness and strong potential for metastasis. We therefore studied the influence of syntenin on the invasivene...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kim, Wook Youn, Jang, Ji-young, Jeon, Yoon Kyung, Chung, Doo Hyun, Kim, Young Goo, Kim, Chul-Woo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972791/
https://ncbi.nlm.nih.gov/pubmed/24722482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2014.1
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