Simultaneous deletion of floxed genes mediated by CaMKIIα-Cre in the brain and in male germ cells: application to conditional and conventional disruption of Goα

The Cre/LoxP system is a well-established approach to spatially and temporally control genetic inactivation. The calcium/calmodulin-dependent protein kinase II alpha subunit (CaMKIIα) promoter limits expression to specific regions of the forebrain and thus has been utilized for the brain-specific in...

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Detalhes bibliográficos
Main Authors: Choi, Chan-Il, Yoon, Sang-Phil, Choi, Jung-Mi, Kim, Sung-Soo, Lee, Young-Don, Birnbaumer, Lutz, Suh-Kim, Haeyoung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972788/
https://ncbi.nlm.nih.gov/pubmed/24787734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2014.14
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