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Steady-state kinetic mechanism of LodA, a novel cysteine tryptophylquinone-dependent oxidase

LodA is a novel lysine-ε-oxidase which possesses a cysteine tryptophylquinone cofactor. It is the first tryptophylquinone enzyme known to function as an oxidase. A steady-state kinetic analysis shows that LodA obeys a ping-pong kinetic mechanism with values of k(cat) of 0.22±0.04 s(−1), K(lysine) of...

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Bibliografski detalji
Glavni autori: Sehanobish, Esha, Shin, Sooim, Sanchez-Amat, Antonio, Davidson, Victor L.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972763/
https://ncbi.nlm.nih.gov/pubmed/24462691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2014.01.021
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