ELISPOT Refinement Using Spot Morphology for Assessing Host Responses to Tuberculosis

Tuberculosis is a global health problem. The Mycobacterium bovis Bacille Calmette Guerin (BCG) vaccine has variable efficacy (0-80%) so there is a drive to develop novel vaccines. The cytokine, interferon gamma (IFNγ), is an essential component of the protective response to M. tuberculosis (M. tb) i...

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Main Authors: Sibley, Laura S., White, Andrew D., Marriott, Alice, Dennis, Michael J., Williams, Ann, Marsh, Philip D., Sharpe, Sally A.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972643/
https://ncbi.nlm.nih.gov/pubmed/24710359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells1010005
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