Transfer RNA is an essential component of the ubiquitin- and ATP-dependent proteolytic system.

Protein degradation via the nonlysosomal ATP-dependent pathway in rabbit reticulocytes involves a number of components. In the initial event, ubiquitin, an abundant 76-residue polypeptide, becomes covalently linked to the protein substrate in an ATP-requiring reaction. Once marked in this way, the c...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Ciechanover, A, Wolin, S L, Steitz, J A, Lodish, H F
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1985
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397256/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2983338/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.5.1341
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