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Transfer RNA is an essential component of the ubiquitin- and ATP-dependent proteolytic system.

Protein degradation via the nonlysosomal ATP-dependent pathway in rabbit reticulocytes involves a number of components. In the initial event, ubiquitin, an abundant 76-residue polypeptide, becomes covalently linked to the protein substrate in an ATP-requiring reaction. Once marked in this way, the c...

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Autori principali: Ciechanover, A, Wolin, S L, Steitz, J A, Lodish, H F
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1985
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC397256/
https://ncbi.nlm.nih.gov/pubmed/2983338
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