Oral cancer cells may rewire alternative metabolic pathways to survive from siRNA silencing of metabolic enzymes

BACKGROUND: Cancer cells may undergo metabolic adaptations that support their growth as well as drug resistance properties. The purpose of this study is to test if oral cancer cells can overcome the metabolic defects introduced by using small interfering RNA (siRNA) to knock down their expression of...

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Autors principals: Zhang, Min, Chai, Yang D, Brumbaugh, Jeffrey, Liu, Xiaojun, Rabii, Ramin, Feng, Sizhe, Misuno, Kaori, Messadi, Diana, Hu, Shen
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972515/
https://ncbi.nlm.nih.gov/pubmed/24666435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-223
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