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Committed Th1 CD4(+) T cell differentiation blocks pregnancy induced Foxp3 expression with antigen specific fetal loss
Pregnancy stimulates induced Foxp3 expression among maternal CD4(+) T cells with fetal specificity. Although sustained maternal Treg expansion is essential for maintaining fetal tolerance during pregnancy, the necessity for Foxp3(+) cells with fetal specificity remains undefined. Here we demonstrate...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3972488/ https://ncbi.nlm.nih.gov/pubmed/24591368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302678 |
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