Genomic architecture characterizes tumor progression paths and fate in breast cancer patients

Distinct molecular subtypes of breast carcinomas have been identified, but translation into clinical use has been limited. We have developed two platform independent algorithms to explore genomic architectural distortion using array comparative genomic hybridization (aCGH) data to measure 1) whole a...

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Main Authors: Russnes, Hege G., Vollan, Hans Kristian Moen, Lingjærde, Ole Christian, Krasnitz, Alexander, Lundin, Pär, Naume, Bjørn, Sørlie, Therese, Borgen, Elin, Rye, Inga H., Langerød, Anita, Chin, Suet-Feung, Teschendorff, Andrew E., Stephens, Philip J., Månér, Susanne, Schlichting, Ellen, Baumbusch, Lars O., Kåresen, Rolf, Stratton, Michael P., Wigler, Michael, Caldas, Carlos, Zetterberg, Anders, Hicks, James, Børresen-Dale, Anne-Lise
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972440/
https://ncbi.nlm.nih.gov/pubmed/20592421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3000611
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