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Grape seed proanthocyanidins and metformin act by different mechanisms to promote insulin signaling in rats fed high calorie diet

Key pathways like insulin signaling, AMP activated kinase (AMPK) activation and inflammatory signaling are involved in the complex pathological network of hepatic insulin resistance. Our aim is to investigate whether grape seed proanthocyanidins (GSP) and metformin (MET) target any of these pathways...

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Detalhes bibliográficos
Main Authors: Yogalakshmi, Baskaran, Bhuvaneswari, Saravanan, Sreeja, S., Anuradha, Carani Venkatraman
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972396/
https://ncbi.nlm.nih.gov/pubmed/24026800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-013-0210-x
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