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Spatial Quantitation of FISH signals in Diploid versus Aneuploid Nuclei
Fluorescence in situ hybridization (FISH) is the most widely used molecular technique to visualize chromosomal abnormalities. Here, we describe a novel 3D modeling approach to allow precise shape estimation and localization of FISH signals in the nucleus of human embryonic stem cells (hES) undergoin...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3972278/ https://ncbi.nlm.nih.gov/pubmed/24347051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.22426 |
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