Serum Bilirubin Affects Graft Outcomes through UDP-Glucuronosyltransferase Sequence Variation in Kidney Transplantation

BACKGROUND: Oxidative stress is a major mediator of adverse outcome after kidney transplantation. Bilirubin is produced by heme oxygenase-1 (HO-1), catalyzed by UDP-glucuronosyltransferase (UGT1A1), and has potential as an antioxidant. In this study, we investigated the effects of HO-1 and UGT1A1 se...

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Main Authors: Lee, Jung Pyo, Kim, Do Hyoung, Yang, Seung Hee, Hwang, Jin Ho, An, Jung Nam, Min, Sang Il, Ha, Jongwon, Oh, Yun Kyu, Kim, Yon Su, Lim, Chun Soo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972238/
https://ncbi.nlm.nih.gov/pubmed/24690955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093633
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