Translational Regulation of GPx-1 and GPx-4 by the mTOR Pathway

Glutathione peroxidase activity was previously determined to be elevated in lymphocytes obtained from patients treated with the Bcr-Abl kinase inhibitor imatinib mesylate. In order to expand upon this observation, the established chronic myelogenous leukemia cell lines KU812 and MEG-01 were treated...

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Main Authors: Reinke, Emily N., Ekoue, Dede N., Bera, Soumen, Mahmud, Nadim, Diamond, Alan M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972146/
https://ncbi.nlm.nih.gov/pubmed/24691473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093472
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