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A Shrinkage Method for Testing the Hardy-Weinberg Equilibrium in Case-Control Studies

Testing for the Hardy-Weinberg equilibrium (HWE) is often used as an initial step for checking the quality of genotyping. When testing the HWE for case-control data, the impact of a potential genetic association between the marker and the disease must be controlled for otherwise the results may be b...

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Detalhes bibliográficos
Main Authors: Zang, Yong, Yuan, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3972031/
https://ncbi.nlm.nih.gov/pubmed/23934751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21753
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