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Clinical implementation of genetic testing in medicine: a US regulatory science perspective

Heterogeneity of treatment effects in unselected patient populations has stimulated various strategic approaches to reduce variability and uncertainty and improve individualization of drug selection and dosing. The rapid growth of DNA sequencing and related technologies has ramped up progress in int...

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Bibliographic Details
Main Authors: Lesko, Lawrence J, Schmidt, Stephan
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971977/
https://ncbi.nlm.nih.gov/pubmed/24286486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12299
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