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Scrapie and Creutzfeldt-Jakob disease prion proteins share physical properties and antigenic determinants.

Scrapie of sheep and goats as well as Creutzfeldt-Jakob disease (CJD) of humans are neurologic disorders caused by slow infectious pathogens. The novel molecular properties of the pathogen causing scrapie have prompted introduction of the term "prion" to denote a small proteinaceous infectious parti...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Bendheim, P E, Bockman, J M, McKinley, M P, Kingsbury, D T, Prusiner, S B
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1985
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397180/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2579394/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.4.997
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