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Demonstration and affinity labeling of a stereoselective binding site for a benzomorphan opiate on acetylcholine receptor-rich membranes from Torpedo electroplaque.

The interaction of an optically pure benzomorphan opiate, (-)-N-allyl-N-normetazocine [(-)-ANMC], with the nicotinic acetylcholine receptor from Torpedo electroplaque was studied by using radioligand binding and affinity labeling. The binding was complex with at least two specific components having...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Oswald, R E, Pennow, N N, McLaughlin, J T
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397163/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3856242/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.3.940
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