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A randomised, controlled, double-blind, cross-over pilot study assessing the effects of spironolactone, losartan and their combination on heart rate variability and QT dispersion in patients with chronic heart failure

BACKGROUND AND OBJECTIVE: The blocking of aldosterone or angiotensin II receptors improves mortality in patients with chronic heart failure. We explored whether combining losartan and spironolactone would have any added benefit on the known surrogate of mortality by using heart rate variability (HRV...

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Detalhes bibliográficos
Main Authors: Shehab, A, Elnour, AA, Struthers, AD
Formato: Artigo
Idioma:Inglês
Publicado em: Clinics Cardive Publishing 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971616/
https://ncbi.nlm.nih.gov/pubmed/19104723
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