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The liver excretes large amounts of heme into bile when heme oxygenase is inhibited competitively by Sn-protoporphyrin.

TinIV-protoporphyrin IX (Sn-protoporphyrin) potently inhibits heme degradation to bilirubin in vitro and in vivo, and it completely suppresses neonatal hyperbilirubinemia in experimental animals, including primates. It also reduces plasma bilirubin levels in certain naturally occurring or induced fo...

詳細記述

保存先:
書誌詳細
主要な著者: Kappas, A, Simionatto, C S, Drummond, G S, Sassa, S, Anderson, K E
フォーマット: Artigo
言語:Inglês
出版事項: 1985
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC397154/
https://ncbi.nlm.nih.gov/pubmed/3856238
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