Naltrexone with or without guanfacine for preventing relapse to opiate addiction in St.-Petersburg, Russia

BACKGROUND: Stress is a key precipitant to discontinuing naltrexone and relapsing to opiate abuse. Alpha-2 adrenergic agonists like guanfacine may reduce stress induced craving and have reduced opiate relapse in small clinical trials. METHODS: This randomized, double blind double dummy placebo-contr...

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Main Authors: Krupitsky, Evgeny, Zvartau, Edwin, Blokhina, Elena, Verbitskaya, Elena, Tsoy, Marina, Wahlgren, Valentina, Burakov, Andrey, Masalov, Dimitry, Romanova, Tatyana N., Palatkin, Vladimir, Tyurina, Arina, Yaroslavtseva, Tatyana, Sinha, Rajita, Kosten, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971535/
https://ncbi.nlm.nih.gov/pubmed/23683793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drugalcdep.2013.04.021
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