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Aberrant Crypt Foci as Precursors in Colorectal Cancer Progression
Colorectal cancer progression originates when accumulated genetic and epigenetic alterations cause genomic instability and a malignant phenotype. Subsequent molecular pathway deregulation leads to histopathologic changes that are clinically evident as aberrant crypt foci (ACF) and visualized by high...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3971525/ https://ncbi.nlm.nih.gov/pubmed/18623110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jso.21106 |
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