Aberrant Crypt Foci as Precursors in Colorectal Cancer Progression

Colorectal cancer progression originates when accumulated genetic and epigenetic alterations cause genomic instability and a malignant phenotype. Subsequent molecular pathway deregulation leads to histopathologic changes that are clinically evident as aberrant crypt foci (ACF) and visualized by high...

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Bibliographic Details
Main Authors: Orlando, Frank A., Tan, Dongfeng, Baltodano, Juan D., Khoury, Thaer, Gibbs, John F., Hassid, Victor J., Ahmed, Bestoun H., Alrawi, Sadir J.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971525/
https://ncbi.nlm.nih.gov/pubmed/18623110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jso.21106
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