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Mapping the Human Reference Genome’s Missing Sequence by Three-Way Admixture in Latino Genomes

A principal obstacle to completing maps and analyses of the human genome involves the genome’s “inaccessible” regions: sequences (often euchromatic and containing genes) that are isolated from the rest of the euchromatic genome by heterochromatin and other repeat-rich sequence. We describe a way to...

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Autori principali: Genovese, Giulio, Handsaker, Robert E., Li, Heng, Kenny, Eimear E., McCarroll, Steven A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971454/
https://ncbi.nlm.nih.gov/pubmed/23932108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.07.002
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