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All-optical osteotomy to create windows for transcranial imaging in mice

Surgical procedures as a prelude to optical imaging are a rate-limiting step in experimental neuroscience. Towards automation of these procedures, we describe the use of nonlinear optical techniques to create a thinned skull window for transcranial imaging. Metrology by second harmonic generation wa...

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Autori principali: Jeong, Diana C., Tsai, Philbert S., Kleinfeld, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: Optical Society of America 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971057/
https://ncbi.nlm.nih.gov/pubmed/24104230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/OE.21.023160
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