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Secondary structure of the circular form of the Tetrahymena rRNA intervening sequence: a technique for RNA structure analysis using chemical probes and reverse transcriptase.

The structure of the intervening sequence (IVS) of the Tetrahymena rRNA precursor mediates cleavage-ligation reactions that result in pre-rRNA splicing and IVS cyclization. We have developed a method for RNA structure analysis and applied it to the circular form of the IVS RNA. The native RNA was tr...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Inoue, T, Cech, T R
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397102/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2579378/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.3.648
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