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In situ enzymatic reclosure of opened imidazole rings of purines in DNA damaged by gamma-irradiation.
When aqueous solutions of DNA were treated with 10-500 grays of gamma-rays, the imidazole rings of some adenine and guanine residues underwent scission, resulting in the conversion of these purines to formamidopyrimidines. It was found that formamidopyrimidine-DNA glycosylase, known to remove imidaz...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1985
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC397099/ https://ncbi.nlm.nih.gov/pubmed/3856219 |
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