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In situ enzymatic reclosure of opened imidazole rings of purines in DNA damaged by gamma-irradiation.

When aqueous solutions of DNA were treated with 10-500 grays of gamma-rays, the imidazole rings of some adenine and guanine residues underwent scission, resulting in the conversion of these purines to formamidopyrimidines. It was found that formamidopyrimidine-DNA glycosylase, known to remove imidaz...

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Bibliografiske detaljer
Main Authors: Chetsanga, C J, Grigorian, C
Format: Artigo
Sprog:Inglês
Udgivet: 1985
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC397099/
https://ncbi.nlm.nih.gov/pubmed/3856219
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