Radiotherapy-Induced Anti-Tumor Immunity Contributes to the Therapeutic Efficacy of Irradiation and Can Be Augmented by CTLA-4 Blockade in a Mouse Model

PURPOSE: There is growing evidence that tumor-specific immune responses play an important role in anti-cancer therapy, including radiotherapy. Using mouse tumor models we demonstrate that irradiation-induced anti-tumor immunity is essential for the therapeutic efficacy of irradiation and can be augm...

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Main Authors: Yoshimoto, Yuya, Suzuki, Yoshiyuki, Mimura, Kousaku, Ando, Ken, Oike, Takahiro, Sato, Hiro, Okonogi, Noriyuki, Maruyama, Takanori, Izawa, Shinichiro, Noda, Shin-ei, Fujii, Hideki, Kono, Koji, Nakano, Takashi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970971/
https://ncbi.nlm.nih.gov/pubmed/24686897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092572
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